uridine相关论文
Development of an eco-friendly and fast HPLC method for quantit-ative analysis of four nucleosides i
An cco-friendly and fast HPLC method was developed for the determination of adenosine,inosine,guanosine and urid-ine in ......
Antiepileptic effect of uridine may be caused by regulating dopamine release and receptor expression
Uridine is a potential endogenous neuromodulator studied for several decades for its antiepileptic effect,but the result......
H/ACA ribonucleoprotein particles (RNPs), the most complicated RNA pseudouridylases, use H/ACA guide RNA for substrate c......
在900~1500 cm-1波段范围内,检测了尿嘧啶核苷水溶液的CARS谱。由于采用了位相失匹配方法,从而消除了非共振背景,由此确定了碱基环骨架......
H/ACA ribonucleoprotein particles (RNPs)(Figure 1(a)), the most complicated RNA pseudouridylases, use H/ACA guide RN......
目的:建立同时测定赤子爱胜蚓药材中尿嘧啶、次黄嘌呤、黄嘌呤、尿苷、腺苷含量的方法。方法:采用高效液相色谱法。色谱柱为Venusi......
目的:建立同时测定十味板蓝根颗粒中尿苷、腺苷、表告依春、靛玉红含量的方法。方法:采用超高效液相串联质谱法(UPLC-MS/MS)。色谱......
目的采用HPLC测定半夏中尿苷、鸟苷和腺苷的含量。方法采用Hypersil ODS(5μm,4.6 mm×250 mm)色谱柱,柱温30℃,流动相为甲醇-水,......
设计合成了氟化并环核苷衍生物3’-氟-2’-O,3’-C-乙烯基键联的并环尿苷(1),并通过1H NMR,13C NMR和HRMS分析表征了其结构.同时,......
以已知核苷为标样,利用高效液相色谱法对冬虫夏草生药及冬虫夏草无性型菌株——中国被毛孢RCEF0273发酵液中核苷类化学成分进行定量......
尿苷用途广泛,发酵法是尿苷研究和生产的主流。以枯草芽孢杆菌F126为实验菌株,首先通过PB实验确定了培养基中影响尿苷产量的最显著......
目的 分别建立HPLC外标法测定地黄药材及其制剂中尿苷和腺苷含量的方法.方法 采用Thermo C18柱(250 mm×4.6 mm,5 μm),尿苷以5 ......
Induction of Recombinant Uridine Phosphorylase and Its Application in Biosynthesis of Pyrimidine Nuc
Recombinant Escherichia coli pUDP,它 overexpressed uridine phosphorylase (UPase ) ,被构造。0.5 mmol 拙粹茨? 0......
从泽泻(Alisma orientalis(Sam.)Juzep)块茎中分离得到六个化合物,经理化性质和波谱分析,分别鉴定为:胡萝卜甙(1),1-二十二醇(2)。尿嘧啶核苷......
目的 研究猫爪草中的化学成分。方法用各种色谱方法分离猫爪草中的化学成分,用理化常数和波谱技术对分离的化合物进行结构鉴定。结......
摘要 [目的]建立简单、快速同时分析黑木耳中腺苷及尿苷含量的HPLC法。[方法]采用Venusil XBP C18色谱柱,流动相为甲醇-水(15:85),流速......
本论文中利用液相寡肽合成方法合成出三种寡肽,将把合成出的寡肽与尿嘧啶核苷相连得到以下尿嘧啶苷的衍生物:BOC-Afg(ToS)Gly-O-2......
目的建立HPLC法同时测定西藏产冬虫夏草中尿苷及腺苷的含量。方法采用Agilent EclipseXDB-C18(250 mm×4.6 mm,5μm)色谱柱,检测......
分析5个不同品种泰山人工北虫草中主要核苷类成分的含量并比较其差异.采用反相高效液相色谱(RP-HPLC)法检测5个样品中尿苷、腺苷、虫......
以尿苷为原料,经丙酰溴酰化保护的同时溴化得到2’-溴代-3',5'-O-二丙酰基尿苷,再由甲酸铵-Pd/C催化氢转移脱溴氢解,最后氨气皂化制......
目的:建立同时测定康复新液中尿苷和黄嘌呤含量的方法。方法:采用HPLC法,Diamonsil C18(250mm×4.6 mm,5μm)色谱柱,甲醇-水(5:95)作为......
目的:研究滴水珠炮制前、后化学成分的变化。方法:采用不同方法对滴水珠生品进行炮制,对其主要成分进行含量测定,并对生品和炮制品的......
目的:建立同时测定盐酸阿糖胞苷原料药的含量和有关物质的方法。方法:采用超高效液相色谱法。色谱柱为Inertsil ODS-3 C18流动相为磷......
核苷类化合物具有抗病毒和抗肿瘤活性,为了寻找高效低毒的抗病毒和抗肿瘤药物,以生物体内源性物质RNA的单体核苷酸尿嘧啶核苷为先导......
目的采用高效液相色谱法同时测定冬虫夏草中尿苷和腺嘌呤2个成分的含量。方法采用Kromasil C18柱(150mm×4.6mm,5μm),以甲醇-水......
目的建立测定不同产地的灵芝提取物(包括赤芝提取物和紫芝提取物)中尿苷和腺苷含量的反相高效液相色谱法。方法采用Agilent Zorbax S......
目的:测定黑柄炭角菌不同组织(天然菌核、天然子座、栽培子座以及发酵菌丝)中的核苷种类及含量。方法:以YWGC18(4.0mm×300mm,10μm......
采用RP-HPLC法测定注射用卡铂的含量,色谱柱:YWG-C18柱,流动相为纯水,检测波长210nm用尿苷作内标,在上述条件下,卡铂和尿苷保留时间分别为6.5min和10.5min且分离良好(R〉1.5),方法......
以三氯氧磷为磷酰化试剂,与尿嘧啶核苷反应,将所得中间产物尿苷磷酰二氯进行胺解,生成具有抗病毒活性的尿苷磷酰胺化合物,目标化合物结......
报道尿苷2-烷基(酰基)-1,3-甘油硫代环磷酸酯的合成,用碘活化的六乙基亚磷酰三胺作为磷酸化试剂,分离得到了硫代环磷酸酯的两个顺反异构体。初......
设计合成了氟化并环核苷衍生物3’-氟-2'-O,3'-C.乙烯基键联的并环尿苷(1),并通过1HNMR,13CNMR和HRMS分析表征了其结构.同时,对具有乙炔基及......
目的:建立同时测定蝉花中肌苷、尿苷含量的方法。方法:采用Shim-pack XP-ODSⅢ(1.6μm,75 mm×2.0 mm)为色谱柱,甲醇-水(5∶95......
目的建立分析北虫草中多糖和核苷类成分含量的方法,并对比分析北虫草子座和培养基中的成分。方法用硫酸.苯酚法测定北虫草中多糖含量......
Chemically Modified Uridine Molecules Incorporating Acyl Residues to Enhance Antibacterial and Cytot
A new N-acetylsulfanilylation series of uridine have been synthesized in good yield using direct acylation method and af......
Chemically Modified Uridine Molecules Incorporating Acyl Residues to Enhance Antibacterial and Cytot
A new N-acetylsulfanilylation series of uridine have been synthesized in good yield using direct acylation method and af......
Symptomatic improvement in an acute, non-traumatic spine pain model with a combination of uridine tr
Rationale: In a previously published trial on spinal acute non-traumatic pain, peripheral neuro- regenerative combinatio......
Background: Gilbert syndrome (GS) is characterized by an elevated serum bil-irubin due to a polymorphism in Uridine Diph......
Genetic analysison the association between polymorphisms of UGT1A1 and GST and neonatal hyperbilirub
Objective:To investigate whether polymorphisms of uridine diphosphoglucuronate-glucuronosyltransferase 1A1(UGT1A1)c.211G......
目的建立用HPLC法测定不同方法(熏干、新鲜和阴干)处理冬虫夏草样品中核苷类成分(腺苷、尿苷、肌苷、鸟苷和胸苷)含量的方法。方法样品......
OBJECTIVE There is growing evidence that uridine may act as an endogenous neuromodulator with a potential signaling role......
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以已知核苷为标样,并以冬虫夏草做对比,利用反相高效液相色谱法对古尼虫草及其发酵菌丝体的核苷类化学成分进行了分析,结果表明古......
Tobacco smoking and its drug interactions with comedications involving CYP and UGT enzymes and nicot
Tobacco smoking is a global public health threat causing several illnesses including cardiovascular disease(Myocardial i......